Senior/ Operations Supervisor (HBV Product Transfer)

The Senior/ Operations Supervisor will support the set-up of the end-to-end production operations within the manufacturing facility so as to achieve productivity targets and objectives in a reliable, efficient and cost-effective manner, and meeting Quality and Health, Safety and Environment (HSE) regulations and other regulatory standards.

The Senior/ Operations Supervisor is a First Line Leader (FLL) serving the following key functions:

1. Management / Supervisory of the team of biotechnologist

• Leading the team in completion of operation steps, delivery of batches and project deliverables

• Provide guidance to the team of biotechnologists

• Take sound technical decision with respect to process issues occurring on the shopfloor

2. First Line Technical Expertise

• Provide technical expertise on the shopfloor to the team of biotechnologists

• Assist in troubleshooting and investigation of issues that happened on the shopfloor

• Ensure the development of technical competency of biotechnologists

• To provide process and technical support in transferring operations and technology for Hepatitis B (HBV) drug substances product manufacture from current production site in Belgium RX59 to Singapore (SG) Tuas.

This role reports to the Operations Lead and will support him/her in any other tasks assigned.

Responsibilities

1. Operations Management

• Responsible to support the set-up of the end-to-end production operations within the future manufacturing facility. Manufacturing activities include:

  - Preparation and Supply of media, buffers and materials

  - Manufacturing of intermediates and drug substance

• Optimize the utilization of capacity and manufacturing resource with sustain efficiency in:

  - Facility

  - Manpower

  - Process

• Adhere to cGMP and safety requirements

• Meet project milestones and deliverables, e.g:

  Participate & Execute Commissioning and Qualification activities

  Small equipment sourcing and material introduction

  Collate process information to support process design

  Design and draft relevant document, e.g SOP, Checklist, OJT and WRA

• Identify areas for improvement and participate in continuous improvement projects to enhance operational effectiveness and efficiency

• Carry out other related duties as assigned by N+1

2. Planning / Schedule

• Adherence to project timeline

3. Management

• Ensure the morale, discipline and well being of the team are well managed and taken care of

• Ensure timely intervention and escalation of any potential conflicts and misunderstanding between team members

• Monitor, plan and coordinate resources to ensure effective utilization of operational staff

• Conduct performance review and development discussion sessions to provide timely performance feedback to N-1 as well as supporting individuals in team to achieve career aspiration

• Ensure team performance in delivering project deliverables

• Ensure in place in use of GSK Production System (GPS), e.g Tier 1 board with KPI adherence, with the team

• Ensure Capacity Management (CAPMAN), Continuous Improvement (CI), issues reporting and escalation, etc are in place in use for the team

• Act as backup to run the process on the shopfloor when there are manpower shortages

4. Leadership (Senior Shift Supervisor)

• Coach and provide guidance to the Shift Supervisor / biotechnologists in the production team in their execution of tasks

• To assist the Operations Lead in ensuring the quality and delivery of tasks

5. Technology Transfer

• Participate in new technology and / or new process transfer

6. Environment, Health, Safety and Wellness

• Ensure safe and secure operations in the facility

• Identify and resolve potential safety issues or risks together with the team

• Support and facilitate safety audits and follow up on the recommendations and Corrective Actions (CAPA)

• Responsible as the primary work permit approver for respective area

7. Training and Development

• Ensure that all biotechnologists are trained in accordance to the training matrix

• To provide support and guidance to new joiner, ensuring their smooth transition to the new environment

• Develop oneself as process Subject Matter Expert (SME)

• Guide junior employees to ensure knowledge transfer for business continuity

• Assist in conducting on-the-job training of the team

8. Interface with Other Department / Team

• Develop good relationship within the team and with other departments (including MSAT, QA, QC, TS, etc) to ensure timely delivery of objectives

Knowledge, Skills & Experience

• DIPLOMA / DEGREE in any Engineering and Science related discipline

• At least 10 years of experience in a pharmaceutical manufacturing plant as manufacturing technician or graduate with minimum 4 years of relevant working experience

• Downstream purification and Chromatography experience

• Basic knowledge of cGMP and Safety issue management

• Knowledge in SAP transaction

• Knowledge in biotechnology equipment

• Good troubleshooting skills

• People management skill

• Effective communication skill

• Effective organization skill

• Continuous improvement mindset

• Strong conflict management skill

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.