Senior Analytical Scientist/ Principal Analytical Scientist

We are looking to fill a new Analytical Scientist position in the GSK Global Manufacturing Science and Technology (MSAT) Analytical Science Asia Hub as part of our expanded remit to support GSK Vaccines. As an Analytical Scientist in the Asia Hub, you are part of the Global Analytical Science team encompassing analytical scientists and materials science experts all over the world covering 3 modalities (small molecule, large molecule and vaccines) in the Global Supply Chain (GSC). In this role, you will focus on leading/ supporting the set-up and qualification of a state-of-the art analytical laboratory and implementation of cutting-edge, advanced analytical technologies for vaccines drug substances and intermediates from pre-launch to late product lifecycle, with potential opportunities to flex, learn and impact across different parts of the business.

• Analytical Leadership and Innovation: Spearhead the full spectrum of analytical activities, including setting up advanced equipment, analytical method technology transfer and optimization, non-routine characterization and comparability assessments of drug substances and intermediates to support new and established vaccines products. These include providing matrix leadership, leading and presenting characterization programs, projects and results to global stakeholders/ partners.

• Data-Driven Insights and Recommendations: Pro-actively generate and interpret comparability data of drug substances/ intermediates as part of material and process changes/ improvements to drive high impact, data-driven recommendations for the optimization of manufacturing processes to improve right first-time performance, product quality, robustness, cost savings and manufacturability.

• Problem-Solving and Root Cause Analysis: Lead laboratory investigations and trouble-shooting related to analytical equipment, methods and out-of-trend results, ensuring timely resolution with effective corrective and preventive actions to minimize business impact and keep projects on track. Provide prompt analytical support for process deviations to minimize impact on security of supply.

• Development of Robust Analytical Strategies: Review and improve analytical methods, procedures and standards in accordance with pharmacopoeia requirements and in-house analytical technical standards, ensuring robust analytical method performance throughout the product lifecycle for both new and established products.

• Analytical Equipment Stewardship: Qualification and lifecycle maintenance (including preventive maintenance/ calibration and performance verification checks) of cutting-edge analytical equipment to appropriate analytical standards aligned with data criticality. Ensure robustness and reliability of analytical equipment in line with GMP and data management principles, mitigating data integrity risks.

• Lifecycle Data Management: Ensure thorough, complete and accurate documentation of all laboratory procedures and data, including standard operating procedures, work instructions, protocols, reports, laboratory notebooks, technical memos, raw data and risk assessments. Maintain compliance to GMP and GLP requirements ensuring data traceability and easy retrieval.

• Champion for Laboratory Safety and Sustainability: Lead/ support environmental health, safety and sustainability activities for the laboratory. Ensure a safe laboratory working environment and inspection readiness of the laboratory through management monitoring (MM)/ independent business monitoring (IBM) inspections, regular safety GEMBA(s) and risk assessments for all analytical activities carried out.

• Mentorship and Development: Supervise, train and develop interns and junior scientists, fostering a culture of safety, compliance and excellence in laboratory practices and data generation.   

• At least a degree in Pharmacy, Chemistry, Pharmaceutical Sciences, Biochemistry/ Biotechnology, Biomedical Engineering or equivalent.

• Extensive hands-on experience in an analytical environment, preferably in the pharmaceutical industry with understanding of GMP and GLP requirements or equivalent.

• Prior experience (min 5 years) in analytical technologies for the analysis and characterization of biologics or vaccines is required.

• Experience in small molecules or material science analytics or an interest in learning more about these is a plus.

• Hands-on experience, skilled in the execution, optimization and trouble-shooting in one or more of the following analytical techniques is preferred: Chromatographic techniques (ultra-performance liquid chromatography with charged aerosol detection, size-exclusion chromatography with multi-angle light scattering, gas chromatography), chemiluminesence techniques, analysis of biomolecular interactions by bio-layer interferometry, fluorescence-based assays, spectrophotometric techniques and colorimetric assays, dynamic light scattering, ELISA immunoassay, chemical analysis (lipid/ polysaccharide content by spectrophotometry, Lowry assay) and molecular biology techniques (polymerase chain reaction).

• Basic knowledge of drug substance and/ or drug product manufacturing processes for vaccines products is preferred.

• Enjoy working in a laboratory environment and thrive in activities and tasks related to analytical method development, troubleshooting, optimization, problem solving and root cause analysis under time pressure, to meet business needs and project implementation timelines.

• Excellent inter-personal communication skills, proactive with leadership skills, data-driven decision making, project management and stakeholder management skills with the experience and ability to work in cross-functional and global teams (across R&D, quality and global analytical hubs).

• Possess a continuous improvement mindset and be able to lead improvement initiatives.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.